HETEs ARE BOUND TO AGP AND CONTRIBUTE TO THE AGP PROVOKED INTRACELLULAR SIGNALLING

............................................................. 4 POPULÄRVETENSKAPLIG SAMMANFATTNING............ 5 ABBREVIATIONS...................................................... 6 BACKGROUND......................................................... 8 INFLAMMATION.......................................................... 8 POLYMORPHONUCLEAR GRANULOCYTES................... 9 CAPTURE AND EXTRAVASATION OF NEUTROPHILS IN THE BLOODSTREAM......................... 10 NEUTROPHIL PHAGOCYTOSIS AND KILLING OF MICROORGANISMS.................................. 12 NEUTROPHIL CARBOHYDRATEBINDING PROTEINS.................................................. 12 L-SELECTIN.................................................... 13 SIGLECS......................................................... 14 S100A8 AND S100A9.......................................... 16 THE ACUTE PHASE RESPONSE................................ 16 ACUTE PHASE PROTEINS.......................................... 17 AGP.................................................................... 17 AGP EXPRESSION.................................................... 17 AGP STRUCTURE..................................................... 17 AGP GLYCAN STRUCTURE......................................... 18 AGP AS A TRANSPORT PROTEIN................................. 19 AGP AS AN IMMUNOMODULATOR............................... 20 AGP AND NEUTROPHILS.................................... 20